CLINICAL WEBSITES

Metformin use reduces risk of death for patients with COVID-19 and diabetes, study finds 2021-01-14
Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a new study. Diabetes is a significant comorbidity for COVID-19. This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or […]
COVID-19 reduced U.S. life expectancy, especially among Black and Latino populations 2021-01-14
A new study finds that due to COVID-19 deaths last year, life expectancy at birth for Americans will shorten by 1.13 years to 77.48 years -- the largest single-year decline in life expectancy in at least 40 years.
Flip the script: Cardiac rehabilitation is underused, but a simple change could fix that 2021-01-14
Making doctors opt out from prescribing cardiac rehabilitation instead of opting in increased referrals by roughly 70 percent
Toadlet peptide transforms into a deadly weapon against bacteria 2021-01-14
Researchers have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.
Cancer models created by mechanical engineers offer new insight into tumor growth 2021-01-14
Engineers have developed in vitro -- in the lab -- lymphatic vessel model to study the growth of tumor emboli, collections of tumor cells within vessels that are often associated with increased metastasis and tumor recurrence.
Population density and virus strains will affect how regions can resume normal life 2021-01-14
As a new, apparently more transmissible version of the virus that causes COVID-19 has appeared in several countries, new research finds that the transmissibility of viral strains and the population density of a region will play big roles in how vaccination campaigns can help towns and cities return to more normal activities. The findings suggest […]
Reverse engineering 3D chromosome models for individual cells 2021-01-14
A new computational technique that uses heat map data to reverse engineer highly detailed models of chromosomes and researchers have uncovered new information about the close spatial relationships that chromatin folding creates between genes.
Feces and algorithms: Artificial Intelligence to map our intestinal bacteria 2021-01-14
The intestines and their bacteria are sometimes called our 'second brain', but studying these bacteria in their natural environment is difficult. Now researchers have developed a method that uses artificial intelligence to map intestinal bacteria using feces. The researchers thus hope to gain more knowledge of the role played by these bacteria in various diseases.
Biochemical pathway that protects cells from ferroptosis discovered 2021-01-14
In an article published in Cell Metabolism, Moffitt Cancer Center researchers report on a newly discovered biochemical pathway that protects cells from a type of cell death called ferroptosis.
Physical frailty syndrome: A cacophony of multisystem dysfunction 2021-01-14
Aging experts synthesize converging evidence that the aging-related pathophysiology underpinning the clinical presentation of phenotypic frailty is a state of lower functioning due to severe dysregulation of the complex dynamics in our bodies that maintains health and resilience. When severity passes a threshold, the clinical syndrome and its phenotype are diagnosable. This paper summarizes evidence […]
The richer you are, the more likely you'll social distance, study finds 2021-01-14
The higher a person's income, the more likely they were to protect themselves at the early stages of the COVID-19 pandemic in the United States, economists find.
Physical virology shows the dynamics of virus reproduction 2021-01-14
The reproductive cycle of viruses requires self-assembly, maturation of virus particles and, after infection, the release of genetic material into a host cell. New physics-based technologies allow scientists to study the dynamics of this cycle and may eventually lead to new treatments.
Deep learning outperforms standard machine learning in biomedical research applications 2021-01-14
Compared to standard machine learning models, deep learning models are largely superior at discerning patterns and discriminative features in brain imaging, despite being more complex in their architecture.
Study demonstrates efficacy of new treatment for neurofibromatosis type 1-related tumors 2021-01-14
Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).
Cancer research reveals how mutations in a specific gene cause different types of disease 2021-01-14
Leading cancer expert solve long-standing question of how various types of mutations in just one gene cause different types of diseases.
Scientists artificially infect mosquitoes with human malaria to advance treatment 2021-01-14
Scientists have identified novel antiplasmodial lead compounds for mass drug administration and vector control to eliminate malaria.
New insight into why breastfed babies have improved immune systems 2021-01-14
Research has revealed new insight into the biological mechanisms of the long-term positive health effects of breastfeeding.
Males of all ages more affected by COVID-19 than females, study finds 2021-01-14
Males are more likely to test positive for COVID-19, more likely to have complications and more likely to die from the virus than females, independent of age, according to a new study.
A rift in the retina may help repair the optic nerve 2021-01-14
In experiments in mouse tissues and human cells, researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged by blinding diseases.
Acting quickly after heart attack symptoms start can be a heart saver 2021-01-14
The degree of heart muscle damage from a heart attack is associated with how long it takes from when heart attack symptoms start to when patients receive an artery-clearing procedure called percutaneous coronary intervention, or PCI. The longer the time period before PCI, called symptom-to-balloon time, the more significant and damaging the heart attack.

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